GM1-ganglioside accumulation at the mitochondria-associated ER membranes links ER stress to Ca(2+)-dependent mitochondrial apoptosis

Mitochondria-associated ER membranes or MAMs define the sites of endoplasmic reticulum/mitochondria juxtaposition that control Ca(2+) flux between these organelles. We found that in a mouse model of the human lysosomal storage disease GM1-gangliosidosis, GM1-ganglioside accumulates in the glycosphin...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Sano, Renata, Annunziata, Ida, Patterson, Annette, Moshiach, Simon, Gomero, Elida, Opferman, Joseph, Forte, Michael, d'Azzo, Alessandra
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782904/
https://ncbi.nlm.nih.gov/pubmed/19917257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.10.021
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items