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The redox-switch domain of Hsp33 functions as dual stress sensor

The redox-regulated chaperone Hsp33 is specifically activated upon exposure of cells to peroxide stress at elevated temperatures. Here we show that Hsp33 harbors two interdependent stress-sensing regions located in the C-terminal redox-switch domain of Hsp33: a zinc center sensing peroxide stress co...

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Detalhes bibliográficos
Main Authors: Ilbert, Marianne, Horst, Janina, Ahrens, Sebastian, Winter, Jeannette, Graf, Paul C F, Lilie, Hauke, Jakob, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782886/
https://ncbi.nlm.nih.gov/pubmed/17515905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1244
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