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Nrf2 Plays an Important Role in Coordinated Regulation of Phase II Drug Metabolize Enzymes and Phase III Drug Transporters
The nuclear transcription factor E2-related factor 2 (Nrf2) has been shown to play pivotal roles in preventing xenobiotics-induced toxicity and carcinogen- related tumorigenesis. These protective effects are mainly attributed to the induction of Phase II drug metabolizing/detoxification and antioxid...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2782863/ https://ncbi.nlm.nih.gov/pubmed/19725016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.680 |
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