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Nrf2 Plays an Important Role in Coordinated Regulation of Phase II Drug Metabolize Enzymes and Phase III Drug Transporters

The nuclear transcription factor E2-related factor 2 (Nrf2) has been shown to play pivotal roles in preventing xenobiotics-induced toxicity and carcinogen- related tumorigenesis. These protective effects are mainly attributed to the induction of Phase II drug metabolizing/detoxification and antioxid...

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Detalhes bibliográficos
Main Authors: Shen, Guoxiang, Kong, Ah-Ng Tony
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782863/
https://ncbi.nlm.nih.gov/pubmed/19725016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdd.680
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