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The 3D Structure of Villin as a Unique F-Actin Crosslinker

Villin is an F-actin nucleating, crosslinking, severing, and capping protein within the gelsolin superfamily. We have used electron tomography of 2D arrays of villin-crosslinked F-actin to generate the first 3D images revealing villin’s crosslinking structure. In these polar arrays, neighboring fila...

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Detalhes bibliográficos
Main Authors: Hampton, Cheri M., Liu, Jun, Taylor, Dianne W., DeRosier, David J., Taylor, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782859/
https://ncbi.nlm.nih.gov/pubmed/19081064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.09.015
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