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Manipulating prohibitin levels provides evidence for an in vivo role in androgen regulation of prostate tumours

Current hormonal therapies for prostate cancer are effective initially, but inevitably tumours progress to an advanced, metastatic stage, often referred to as ‘androgen independent’. However, the androgen receptor (AR) signalling pathway is still key for their growth. It is speculated that tumours e...

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Главные авторы: Dart, D Alwyn, Spencer-Dene, Bradley, Gamble, Simon C, Waxman, Jonathan, Bevan, Charlotte L
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Endocrinology 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782800/
https://ncbi.nlm.nih.gov/pubmed/19635783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/ERC-09-0028
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