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Harnessing CD1d-restricted T cells towards anti-tumor immunity in humans

Natural killer T (NKT) cells are a distinct subset of T cells that recognize lipid antigens in the context of CD1d molecules. There is considerable body of evidence implicating a role for NKT cells in regulating anti-tumor immunity in mice. α-galactosylceramide (α-GalCer) is a potent agonist ligand...

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Detalhes bibliográficos
Main Authors: Neparidze, Natalia, Dhodapkar, Madhav V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782771/
https://ncbi.nlm.nih.gov/pubmed/19769737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.04931.x
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