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Mechanistic analysis of electroporation-induced cellular uptake of macromolecules

Pulsed electric field has been widely used as a non-viral gene delivery platform. The delivery efficiency can be improved through quantitative analysis of pore dynamics and intracellular transport of plasmid DNA. To this end, we investigated mechanisms of cellular uptake of macromolecules during ele...

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Bibliographic Details
Main Authors: Zaharoff, David A., Henshaw, Joshua W., Mossop, Brian, Yuan, Fan
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782745/
https://ncbi.nlm.nih.gov/pubmed/18156311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3181/0704-RM-113
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