Imidazole Metalloporphyrins as Photosensitizers for Photodynamic Therapy: Role of Molecular Charge, Central Metal and Hydroxyl Radical Production

The in vitro photodynamic therapy activity of four imidazole-substituted metalloporphyrins has been studied using human (HeLa) and mouse (CT26) cancer cell lines: an anionic Zn porphyrin and a homologous series of three cationic Zn, Pd or InCl porphyrins. A dramatic difference in phototoxicity was f...

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Main Authors: Mroz, Pawel, Bhaumik, Jayeeta, Dogutan, Dilek K., Aly, Zarmeneh, Kamal, Zahra, Khalid, Laiqua, Kee, Hooi Ling, Bocian, David F., Holten, Dewey, Lindsey, Jonathan S., Hamblin, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782654/
https://ncbi.nlm.nih.gov/pubmed/19346065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2009.02.054
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