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Replacement of Lipopolysaccharide with Free Lipid A Molecules in Escherichia coli Mutants Lacking All Core Sugars

Escherichia coli mutants deficient in 2-keto-3-deoxy-d-manno-octulosonic acid (Kdo) biosynthesis are conditionally lethal, but their phenotypes are bypassed by certain suppressor mutations or by over-expression of MsbA, the inner membrane flippase for core-lipid A. These strains grow on broth with t...

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Detalhes bibliográficos
Main Authors: Reynolds, C. Michael, Raetz, Christian R. H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782650/
https://ncbi.nlm.nih.gov/pubmed/19754149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901391g
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