Hypoxia inducible mir-210 regulates normoxic gene expression involved in tumor initiation

Previous studies have suggested that the HIF transcription factors can both activate and inhibit gene expression. Here we show that HIF1 regulates the expression of mir-210 in a variety of tumor types through a hypoxia responsive element. Expression analysis in primary head & neck tumor samples...

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Bibliografiske detaljer
Main Authors: Huang, Xin, Ding, Lianghao, Bennewith, Kevin, Tong, Ricky, Ang, Ki Kian, Story, Michael, Le, Quynh-Thu, Giaccia, Amato J.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782615/
https://ncbi.nlm.nih.gov/pubmed/19782034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.09.006
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