A polymorphism within interleukin-21 receptor (IL21R) confers risk for systemic lupus erythematosus

OBJECTIVE: Interleukin (IL) 21 is a member of the type I cytokine superfamily that exerts a variety of effects on the immune system including B cell activation, plasma cell differentiation, and immunoglobulin production. The expression of IL21R is reduced in B cells from lupus patients, while IL21 s...

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Main Authors: Webb, Ryan, Merrill, Joan T., Kelly, Jennifer A., Sestak, Andrea, Kaufman, Kenneth M., Langefeld, Carl D., Ziegler, Julie, Kimberly, Robert P., Edberg, Jeffrey C., Ramsey-Goldman, Rosalind, Petri, Michelle, Reveille, John D., Alarcón, Graciela S., Vilá, Luis M., Alarcón-Riquelme, Marta E., James, Judith A., Gilkeson, Gary S., Jacob, Chaim O., Moser, Kathy L., Gaffney, Patrick M., Vyse, Timothy J., Nath, Swapan K., Lipsky, Peter, Harley, John B., Sawalha, Amr H.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782592/
https://ncbi.nlm.nih.gov/pubmed/19644854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24658
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