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Protein adsorption and transport in dextran-modified ion-exchange media I. Adsorption

Adsorption behavior is compared on a traditional agarose-based ion-exchange resin and on two dextran-modified resins, using three proteins to examine the effect of protein size. The latter resins typically exhibit higher static capacities at low ionic strengths and electron microscopy provides direc...

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Bibliographic Details
Main Authors: Bowes, Brian D., Koku, Harun, Czymmek, Kirk J., Lenhoff, Abraham M.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782466/
https://ncbi.nlm.nih.gov/pubmed/19801150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2009.09.014
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