Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa

Glycoconjugates expressed on gastric mucosa play a crucial role in host–pathogen interactions. The FUT2 enzyme catalyzes the addition of terminal α(1,2)fucose residues, producing the H type 1 structure expressed on the surface of epithelial cells and in mucosal secretions of secretor individuals. In...

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Detalhes bibliográficos
Main Authors: Magalhães, Ana, Gomes, Joana, Ismail, Mohd Nazri, Haslam, Stuart M, Mendes, Nuno, Osório, Hugo, David, Leonor, Le Pendu, Jacques, Haas, Rainer, Dell, Anne, Borén, Thomas, Reis, Celso A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782244/
https://ncbi.nlm.nih.gov/pubmed/19706747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwp131
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