In Vitro Cutaneous Application of ISCOMs on Human Skin Enhances Delivery of Hydrophobic Model Compounds Through the Stratum Corneum

This study aimed to investigate the effect of a novel kind of immune-stimulating complexes (ISCOMs) on human skin penetration of model compounds in vitro to evaluate their potential as a delivery system, ultimately for transcutaneous vaccination. Special focus was on elucidating the mechanisms of pe...

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Bibliographic Details
Main Authors: Madsen, Henriette Baun, Ifversen, Peter, Madsen, Flemming, Brodin, Birger, Hausser, Ingrid, Nielsen, Hanne Mørck
Format: Artigo
Language:Inglês
Published: Springer US 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782083/
https://ncbi.nlm.nih.gov/pubmed/19862629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-009-9149-5
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