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Molecular Dissection of Erv26p Identifies Separable Cargo Binding and Coat Protein Sorting Activities

Efficient export of secretory alkaline phosphatase (ALP) from the endoplasmic reticulum depends on the conserved transmembrane sorting adaptor Erv26p/Svp26p. In the present study we investigated the mechanism by which Erv26p couples pro-ALP to the coat protein complex II (COPII) export machinery. Si...

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Main Authors: Bue, Catherine A., Barlowe, Charles
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781999/
https://ncbi.nlm.nih.gov/pubmed/19574229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.022590
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