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PKCδ regulates cortical radial migration by stabilizing the Cdk5 activator p35

Cyclin-dependent kinase 5 (Cdk5) and its activator p35 are critical for radial migration and lamination of cortical neurons. However, how this kinase is regulated by extracellular and intracellular signals during cortical morphogenesis remains unclear. Here, we show that PKCδ, a member of novel PKC...

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Detalhes bibliográficos
Main Authors: Zhao, Chun-tao, Li, Kun, Li, Jun-tao, Zheng, Wang, Liang, Xu-jun, Geng, An-qi, Li, Ning, Yuan, Xiao-bing
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781735/
https://ncbi.nlm.nih.gov/pubmed/19965374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812872106
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