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PKCδ regulates cortical radial migration by stabilizing the Cdk5 activator p35

Cyclin-dependent kinase 5 (Cdk5) and its activator p35 are critical for radial migration and lamination of cortical neurons. However, how this kinase is regulated by extracellular and intracellular signals during cortical morphogenesis remains unclear. Here, we show that PKCδ, a member of novel PKC...

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Bibliografske podrobnosti
Main Authors: Zhao, Chun-tao, Li, Kun, Li, Jun-tao, Zheng, Wang, Liang, Xu-jun, Geng, An-qi, Li, Ning, Yuan, Xiao-bing
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781735/
https://ncbi.nlm.nih.gov/pubmed/19965374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812872106
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