Three-way Interaction between 14-3-3 Proteins, the N-terminal Region of Tyrosine Hydroxylase, and Negatively Charged Membranes

Tyrosine hydroxylase (TH), the rate-limiting enzyme in the synthesis of catecholamines, is activated by phosphorylation-dependent binding to 14-3-3 proteins. The N-terminal domain of TH is also involved in interaction with lipid membranes. We investigated the binding of the N-terminal domain to its...

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Hlavní autoři: Halskau, Øyvind, Ying, Ming, Baumann, Anne, Kleppe, Rune, Rodriguez-Larrea, David, Almås, Bjørg, Haavik, Jan, Martinez, Aurora
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781693/
https://ncbi.nlm.nih.gov/pubmed/19801645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.027706
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