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Preferred Sequences within a Defined Cleavage Window Specify DNA 3′ End-directed Cleavages by Retroviral RNases H

The RNase H activity of reverse transcriptase carries out three types of cleavage termed internal, RNA 5′ end-directed, and DNA 3′ end-directed. Given the strong association between the polymerase domain of reverse transcriptase and a DNA 3′ primer terminus, we asked whether the distance from the pr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Schultz, Sharon J., Zhang, Miaohua, Champoux, James J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781635/
https://ncbi.nlm.nih.gov/pubmed/19778906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.043158
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