Crystal Structure and Function of a DARPin Neutralizing Inhibitor of Lactococcal Phage TP901-1: COMPARISON OF DARPin AND CAMELID VHH BINDING MODE

Combinatorial libraries of designed ankyrin repeat proteins (DARPins) have been proven to be a valuable source of specific binding proteins, as they can be expressed at very high levels and are very stable. We report here the selection of DARPins directed against a macromolecular multiprotein comple...

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Detalles Bibliográficos
Autores principales: Veesler, David, Dreier, Birgit, Blangy, Stéphanie, Lichière, Julie, Tremblay, Denise, Moineau, Sylvain, Spinelli, Silvia, Tegoni, Mariella, Plückthun, Andreas, Campanacci, Valérie, Cambillau, Christian
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Protein Structure and Folding
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781625/
https://ncbi.nlm.nih.gov/pubmed/19740746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.037812
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