C-terminal Phenylalanine of Bacteriophage T7 Single-stranded DNA-binding Protein Is Essential for Strand Displacement Synthesis by T7 DNA Polymerase at a Nick in DNA

Single-stranded DNA-binding protein (gp2.5), encoded by gene 2.5 of bacteriophage T7, plays an essential role in DNA replication. Not only does it remove impediments of secondary structure in the DNA, it also modulates the activities of the other replication proteins. The acidic C-terminal tail of g...

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Hlavní autoři: Ghosh, Sharmistha, Marintcheva, Boriana, Takahashi, Masateru, Richardson, Charles C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781589/
https://ncbi.nlm.nih.gov/pubmed/19726688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.024059
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