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Highly Conserved Cysteines within the Ly6 Domain of GPIHBP1 Are Crucial for the Binding of Lipoprotein Lipase

GPIHBP1, a glycosylphosphatidylinositol-anchored endothelial cell protein of the lymphocyte antigen 6 (Ly6) family, binds lipoprotein lipase (LPL) avidly and is required for the lipolytic processing of triglyceride-rich lipoproteins. GPIHBP1 contains two key structural motifs, an acidic domain and a...

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Autori principali: Beigneux, Anne P., Gin, Peter, Davies, Brandon S. J., Weinstein, Michael M., Bensadoun, André, Fong, Loren G., Young, Stephen G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781579/
https://ncbi.nlm.nih.gov/pubmed/19726683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.046391
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