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Proteolytic Cleavage of Type I Collagen Generates an Autoantigen in Autoimmune Uveitis

This study was initiated to induce experimental autoimmune anterior uveitis (EAAU) in Lewis rats by melanin-associated antigen (MAA; 22-kDa fragment of type I collagen α2 chain) derived from rat iris and ciliary body (CB), to localize MAA within the eye, and to investigate the possible mechanism of...

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Détails bibliographiques
Auteurs principaux: Jha, Purushottam, Manickam, Balasubramanian, Matta, Bharati, Bora, Puran S., Bora, Nalini S.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781536/
https://ncbi.nlm.nih.gov/pubmed/19755419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.033381
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