Sterol and Diacylglycerol Acyltransferase Deficiency Triggers Fatty Acid-mediated Cell Death

Deletion of the acyltransferases responsible for triglyceride and steryl ester synthesis in Saccharomyces cerevisiae serves as a genetic model of diseases where lipid overload is a component. The yeast mutants lack detectable neutral lipids and cytoplasmic lipid droplets and are strikingly sensitive...

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Bibliografiske detaljer
Main Authors: Garbarino, Jeanne, Padamsee, Mahajabeen, Wilcox, Lisa, Oelkers, Peter M., D'Ambrosio, Diana, Ruggles, Kelly V., Ramsey, Nicole, Jabado, Omar, Turkish, Aaron, Sturley, Stephen L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781500/
https://ncbi.nlm.nih.gov/pubmed/19690167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.050443
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