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Phospholipid Association Is Essential for Dynamin-related Protein Mgm1 to Function in Mitochondrial Membrane Fusion

Mgm1, the yeast ortholog of mammalian OPA1, is a key component in mitochondrial membrane fusion and is required for maintaining mitochondrial dynamics and morphology. We showed recently that the purified short isoform of Mgm1 (s-Mgm1) possesses GTPase activity, self-assembles into low order oligomer...

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Detalhes bibliográficos
Principais autores: Rujiviphat, Jarungjit, Meglei, Gabriela, Rubinstein, John L., McQuibban, G. Angus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781412/
https://ncbi.nlm.nih.gov/pubmed/19703904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.044933
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