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Maternal nutrient restriction during early fetal kidney development attenuates the renal innate inflammatory response in obese young adult offspring
Obesity is an independent risk factor for developing chronic kidney disease. Toll-like receptor 4 (TLR4), interleukin (IL)-18, and uncoupling protein 2 (UCP2) are important components of the innate immune system mediating inflammatory renal damage. Early to midgestation maternal nutrient restriction...
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Hoofdauteurs: | , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
American Physiological Society
2009
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781328/ https://ncbi.nlm.nih.gov/pubmed/19759269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00303.2009 |
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