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Maternal nutrient restriction during early fetal kidney development attenuates the renal innate inflammatory response in obese young adult offspring

Obesity is an independent risk factor for developing chronic kidney disease. Toll-like receptor 4 (TLR4), interleukin (IL)-18, and uncoupling protein 2 (UCP2) are important components of the innate immune system mediating inflammatory renal damage. Early to midgestation maternal nutrient restriction...

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Bibliografische gegevens
Hoofdauteurs: Sharkey, Don, Gardner, David S., Symonds, Michael E., Budge, Helen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781328/
https://ncbi.nlm.nih.gov/pubmed/19759269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00303.2009
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