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Association of a Single Nucleotide Polymorphism in the C-Reactive Protein Gene (−286) with Susceptibility to Plasmodium falciparum Malaria

The role of inflammation in malaria pathogenesis is not fully understood, although C-reactive protein (CRP) may have a negative influence on host immunity to infections. An upstream polymorphism, −286 (C > T > A), in the CRP gene is known to influence CRP levels. In this study, a cohort of 192...

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Detalhes bibliográficos
Main Authors: Giha, Hayder A, Nasr, Amre, Ekström, Mattias, Israelsson, Elisabeth, Arambepola, Gishanthi, Arnot, David, Theander, Thor G, Troye-Blomberg, Marita, Berzins, Klavs, Tornvall, Per, ElGhazali, Gehad
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781302/
https://ncbi.nlm.nih.gov/pubmed/19946607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2009.00136
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