Tissue Inhibitor of Metalloproteinase 1 Expression Associated with Gene Demethylation Confers Anoikis Resistance in Early Phases of Melanocyte Malignant Transformation

Although anoikis resistance has been considered a hallmark of malignant phenotype, the causal relation between neoplastic transformation and anchorage-independent growth remains undefined. We developed an experimental model of murine melanocyte malignant transformation, where a melanocyte lineage (m...

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Hlavní autoři: Ricca, Tatiana I, Liang, Gangning, Suenaga, Ana Paula M, Han, Sang W, Jones, Peter A, Jasiulionis, Miriam G
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781071/
https://ncbi.nlm.nih.gov/pubmed/19956395
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