Promoter Hypermethylation in Tumor Suppressing Genes p16 and FHIT and Their Relationship with Estrogen Receptor and Progesterone Receptor Status in Breast Cancer Patients from Northern India

BACKGROUND: Aberrant DNA methylation has been recognized in human breast carcinogenesis as a common molecular alteration associated with the loss of expression of a number of key regulatory genes. The present study was undertaken to determine whether methylation and expression of p16 and FHIT genes...

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Main Authors: Raish, Mohammad, Dhillon, Varinderpal S, Ahmad, Arif, Ansari, Mushtaq Ahmad, Mudassar, Shahid, Shahid, Mohammad, Batra, Vineeta, Gupta, Pawan, Das, Bhudev Chandra, Shukla, NK, Husain, Syed Akhtar
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781065/
https://ncbi.nlm.nih.gov/pubmed/19956388
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