B cells and monocytes from patients with active multiple sclerosis exhibit increased surface expression of both HERV-H Env and HERV-W Env, accompanied by increased seroreactivity

BACKGROUND: The etiology of the neurogenerative disease multiple sclerosis (MS) is unknown. The leading hypotheses suggest that MS is the result of exposure of genetically susceptible individuals to certain environmental factor(s). Herpesviruses and human endogenous retroviruses (HERVs) represent po...

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Bibliographische Detailangaben
Hauptverfasser: Brudek, Tomasz, Christensen, Tove, Aagaard, Lars, Petersen, Thor, Hansen, Hans J, Møller-Larsen, Anné
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780989/
https://ncbi.nlm.nih.gov/pubmed/19917105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-6-104
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