Fibroblast Growth Factor-21 Is Induced in Human Skeletal Muscles by Hyperinsulinemia

OBJECTIVE: Fibroblast growth factor-21 (FGF-21) is a potent metabolic regulator, which in animal models has been shown to improve glucose metabolism and insulin sensitivity. Recently, FGF-21 was shown to be expressed and secreted from murine muscle cells in response to insulin stimulation. RESEARCH...

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Autors principals: Hojman, Pernille, Pedersen, Maria, Nielsen, Anders Rinnov, Krogh-Madsen, Rikke, Yfanti, Christina, Åkerstrom, Thorbjørn, Nielsen, Søren, Pedersen, Bente Klarlund
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2009
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780875/
https://ncbi.nlm.nih.gov/pubmed/19720803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0713
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