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Adenovirus E3 MHC inhibitory genes but not TNF/Fas apoptotic inhibitory genes expressed in β cells prevent autoimmune diabetes
To mimic events and molecules involved in type 1 insulin-dependent diabetes mellitus (T1D), we previously designed a transgenic (tg) mouse model where the viral nucleoprotein (NP) gene of lymphocytic choriomeningitis virus (LCMV) was expressed in the thymus to delete high affinity antiself (virus) T...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2780797/ https://ncbi.nlm.nih.gov/pubmed/19887639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910648106 |
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