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Vascular growth factor binding kinetics to the endothelial cell basement membrane, with a kinetics-based correction for substrate binding

Vascular growth factors, including vascular endothelial growth factor and fibroblast growth factor-2, bind to heparan sulfate proteoglycans in the basement membrane. While this binding, storage, and release system provides a critical model for controlled drug release devices, basement membrane—growt...

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Bibliographic Details
Main Authors: Clyne, Alisa Morss, Edelman, Elazer R.
Format: Artigo
Language:Inglês
Published: Springer Netherlands 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780541/
https://ncbi.nlm.nih.gov/pubmed/19639390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-009-9212-1
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