The DEAD box protein p72 regulates ERα-/Estrogen-dependent transcription and cell growth, and is associated with improved survival in ERα positive breast cancer

The DEAD-box RNA helicases p68 (DDX5) and p72 (DDX17) have been shown to act as transcriptional co-activators for a diverse range of transcription factors, including estrogen receptor α (ERα). Here, we show that, although both proteins interact with and co-activate ERα in reporter gene assays, siRNA...

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Hauptverfasser: Wortham, N. C., Ahamed, E., Nicol, S. M., Thomas, R. S., Periyasamy, M., Jiang, J., Ochocka, A. M., Shousha, S., Huson, L., Bray, S. E., Coombes, R. C., Ali, S., Fuller-Pace, F. V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2780396/
https://ncbi.nlm.nih.gov/pubmed/19718048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.261
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