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Aberrant Epigenetic Regulation Could Explain the Relationship of Paternal Age to Schizophrenia

The causal mechanism underlying the well-established relation between advancing paternal age and schizophrenia is hypothesized to involve mutational errors during spermatogenesis that occur with increasing frequency as males age. Point mutations are well known to increase with advancing paternal age...

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Detalhes bibliográficos
Main Authors: Perrin, Mary C., Brown, Alan S., Malaspina, Dolores
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779878/
https://ncbi.nlm.nih.gov/pubmed/17712030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbm093
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