GOLPH3 Bridges Phosphatidylinositol-4- Phosphate and Actomyosin to Stretch and Shape the Golgi to Promote Budding

Golgi membranes, from yeast to humans, are uniquely enriched in phosphatidylinositol-4-phosphate (PtdIns(4)P), although the role of this lipid remains poorly understood. Using a proteomic lipid binding screen, we identify the Golgi protein GOLPH3 (also called GPP34, GMx33, MIDAS, or yeast Vps74p) as...

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Autors principals: Dippold, Holly C., Ng, Michelle M., Farber-Katz, Suzette E., Lee, Sun-Kyung, Kerr, Monica L., Peterman, Marshall C., Sim, Ronald, Wiharto, Patricia A., Galbraith, Kenneth A., Madhavarapu, Swetha, Fuchs, Greg J., Meerloo, Timo, Farquhar, Marilyn G., Zhou, Huilin, Field, Seth J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779841/
https://ncbi.nlm.nih.gov/pubmed/19837035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.07.052
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