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Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been

Sterol regulatory element-binding proteins (SREBPs) are a subfamily of basic helix–loop–helix leucine zipper (bHLH-LZ) transcription factors that are conserved from fungi to humans and are defined by two key features: a signature tyrosine residue in the DNA-binding domain, and a membrane-tethering d...

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Detalhes bibliográficos
Main Authors: Osborne, Timothy F., Espenshade, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779761/
https://ncbi.nlm.nih.gov/pubmed/19933148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1854309
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