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SUMO Modification Regulates BLM and RAD51 Interaction at Damaged Replication Forks
The gene mutated in Bloom's syndrome, BLM, is important in the repair of damaged replication forks, and it has both pro- and anti-recombinogenic roles in homologous recombination (HR). At damaged forks, BLM interacts with RAD51 recombinase, the essential enzyme in HR that catalyzes homology-dep...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779653/ https://ncbi.nlm.nih.gov/pubmed/19956565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000252 |
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