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SUMO Modification Regulates BLM and RAD51 Interaction at Damaged Replication Forks
The gene mutated in Bloom's syndrome, BLM, is important in the repair of damaged replication forks, and it has both pro- and anti-recombinogenic roles in homologous recombination (HR). At damaged forks, BLM interacts with RAD51 recombinase, the essential enzyme in HR that catalyzes homology-dep...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779653/ https://ncbi.nlm.nih.gov/pubmed/19956565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000252 |
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