SUMO Modification Regulates BLM and RAD51 Interaction at Damaged Replication Forks

The gene mutated in Bloom's syndrome, BLM, is important in the repair of damaged replication forks, and it has both pro- and anti-recombinogenic roles in homologous recombination (HR). At damaged forks, BLM interacts with RAD51 recombinase, the essential enzyme in HR that catalyzes homology-dep...

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Bibliographic Details
Main Authors: Ouyang, Karen J., Woo, Leslie L., Zhu, Jianmei, Huo, Dezheng, Matunis, Michael J., Ellis, Nathan A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779653/
https://ncbi.nlm.nih.gov/pubmed/19956565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000252
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