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Comparisons of pKa and log P values of some carboxylic and phosphonic acids: Synthesis and measurement
The changes in the physiochemical properties accompanying the substitution of a phosphonic acid group for a carboxylic acid group on various heterocyclic platforms was determined. A series of low molecular weight heterocyclic carboxylic and phosphonic acids was prepared, and the acid dissociation co...
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| Natura: | Artigo |
| Lingua: | Inglês |
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Springer-Verlag
2001
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2779558/ https://ncbi.nlm.nih.gov/pubmed/11741262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/ps030210 |
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