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Three-dimensional structure of fibrolase, the fibrinolytic enzyme from southern copperhead venom, modeled from the x-ray structure of adamalysin II and atrolysin C

The fibrinolytic enzyme from southern copperhead snake venom, fibrolase, contains 1 mole of zine per mole of protein, belongs to the major family of metalloproteinases known as the metzincins, and has been shown to degrade fibrin clots in vitro and in vivo. The purpose of this study was to develop a...

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Main Authors: Bolger, Michael B., Swenson, Steve, Markland, Francis S.
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779553/
https://ncbi.nlm.nih.gov/pubmed/11741267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/ps030216
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