Cohesinopathy mutations disrupt the subnuclear organization of chromatin

In Saccharomyces cerevisiae, chromatin is spatially organized within the nucleus with centromeres clustering near the spindle pole body, telomeres clustering into foci at the nuclear periphery, ribosomal DNA repeats localizing within a single nucleolus, and transfer RNA (tRNA) genes present in an ad...

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Bibliographic Details
Main Authors: Gard, Scarlett, Light, William, Xiong, Bo, Bose, Tania, McNairn, Adrian J., Harris, Bethany, Fleharty, Brian, Seidel, Chris, Brickner, Jason H., Gerton, Jennifer L.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2009
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779225/
https://ncbi.nlm.nih.gov/pubmed/19948494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200906075
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