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Two adaptor proteins differentially modulate the phosphorylation and biophysics of Kv1.3 ion channel by Src kinase

The Shaker family K(+) channel protein, Kv1.3, is tyrosine phosphorylated by v-Src kinase at Tyr(137) and Tyr(449) to modulate current magnitude and kinetic properties. Despite two proline rich sequences and these phosphotyrosines contained in the carboxyl and amino terminals of the channel, v-Src k...

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Detalhes bibliográficos
Main Authors: Cook, K.K., Fadool, D.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779217/
https://ncbi.nlm.nih.gov/pubmed/11812778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M108898200
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