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Minocycline delayed photoreceptor death in the rds mice through iNOS-dependent mechanism

PURPOSE: To elucidate the role of activated microglia and nitric oxide (NO) in photoreceptor apoptosis in rds mice, and to investigate the effect of minocycline treatment on rds mice. METHODS: Photoreceptor apoptosis in rds mice was detected by terminal dUTP transferase nick end labeling (TUNEL). Re...

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Main Authors: Yang, Li-ping, Li, Ying, Zhu, Xiu-an, Tso, Mark O.M.
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779141/
https://ncbi.nlm.nih.gov/pubmed/17653052
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