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Determinism and divergence of apoptosis susceptibility in mammalian cells

Although the cellular decision to commit to apoptosis is important for organism homeostasis, there is considerable variability in the onset of apoptosis between cells, even in clonal populations. Using live single-cell imaging, we observed that the onset of apoptotic proteolytic activity was tightly...

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Detalhes bibliográficos
Main Authors: Bhola, Patrick D., Simon, Sanford M.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779131/
https://ncbi.nlm.nih.gov/pubmed/19887588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.055590
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