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Quantitative effect of scaffold abundance on signal propagation

Protein scaffolds bring together multiple components of a signalling pathway, thereby promoting signal propagation along a common physical ‘backbone'. Scaffolds play a prominent role in natural signalling pathways and provide a promising platform for synthetic circuits. To better understand how...

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Detalhes bibliográficos
Main Authors: Chapman, Stephen A, Asthagiri, Anand R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779087/
https://ncbi.nlm.nih.gov/pubmed/19888208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.73
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