Phosphatase-Dependent Regulation of Epithelial Mitogen-Activated Protein Kinase Responses to Toxin-Induced Membrane Pores

Diverse bacterial species produce pore-forming toxins (PFT) that can puncture eukaryotic cell membranes. Host cells respond to sublytic concentrations of PFT through conserved intracellular signaling pathways, including activation of mitogen-activated protein kinases (MAPK), which are critical to ce...

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Bibliographic Details
Main Authors: Aguilar, Jorge L., Kulkarni, Ritwij, Randis, Tara M., Soman, Sandeep, Kikuchi, Alexander, Yin, Yuxin, Ratner, Adam J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778951/
https://ncbi.nlm.nih.gov/pubmed/19956644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008076
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