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Investigating the robustness of the classical enzyme kinetic equations in small intracellular compartments

BACKGROUND: Classical descriptions of enzyme kinetics ignore the physical nature of the intracellular environment. Main implicit assumptions behind such approaches are that reactions occur in compartment volumes which are large enough so that molecular discreteness can be ignored and that molecular...

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Detalhes bibliográficos
Autor principal: Grima, Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778647/
https://ncbi.nlm.nih.gov/pubmed/19814817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-3-101
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