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Fulfilling the Promise of Personalized Medicine? Systematic Review and Field Synopsis of Pharmacogenetic Studies

BACKGROUND: Studies of the genetic basis of drug response could help clarify mechanisms of drug action/metabolism, and facilitate development of genotype-based predictive tests of efficacy or toxicity (pharmacogenetics). OBJECTIVES: We conducted a systematic review and field synopsis of pharmacogene...

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Detalhes bibliográficos
Main Authors: Holmes, Michael V., Shah, Tina, Vickery, Christine, Smeeth, Liam, Hingorani, Aroon D., Casas, Juan P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778625/
https://ncbi.nlm.nih.gov/pubmed/19956635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007960
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