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Thrombospondin-2 and SPARC/osteonectin are critical regulators of bone remodeling

Thrombospondin-2 (TSP2) and osteonectin/BM-40/SPARC are matricellular proteins that are highly expressed by bone cells. Mice deficient in either of these proteins show phenotypic alterations in the skeleton, and these phenotypes are most pronounced under conditions of altered bone remodeling. For ex...

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Detalles Bibliográficos
Main Authors: Delany, Anne M., Hankenson, Kurt David
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778593/
https://ncbi.nlm.nih.gov/pubmed/19862642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-009-0076-0
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